Helpers (pH, solvents)

Alcohol denat.

INCI: ALCOHOL DENAT. · also Denatured alcohol, SD alcohol

Drinking alcohol, made undrinkable.

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C2H6O46.07 g/mol
Ethanol: the denaturant added in small amounts is not shown
oxygencarbonhydrogen
3D shape from PubChem 702

How common

All products8.2%
In sunscreens34%
In deodorants28%
In face moisturisers16%

1,208 of 14,784 products with a full ingredient list in Open Beauty Facts; No. 32 of all the names found on their labels.

What it is

  • Ethanol, the alcohol in drinks, with a little of another substance added to make it unfit to drink. The bitter denatonium benzoate works at just 0.0006%.

    3 sourcesHide
    Alcohol Denat. is the generic term used by the cosmetics industry to describe denatured alcohol.[1] US Cosmetic Ingredient Review expert panel · 2008 · open source
    Ethanol with a small amount of an adulterant added so as to be unfit for use as a beverage.[2] PubChem (US National Library of Medicine) · open source
    Denatonium Benzoate is sufficiently bitter that it is an effective denaturant at only 0.0006%.[1] US Cosmetic Ingredient Review expert panel · 2008 · open source
  • Not to be confused with fatty alcohols such as cetearyl alcohol: cetyl alcohol, for one, is a white solid.

    SourceHide
    white solid/odourless[3] PubChem (US National Library of Medicine) · open source

Why it is in products

  • It dissolves other ingredients and evaporates fast, which is why it is common in hair sprays, gels and quick-drying products.

    3 sourcesHide
    Ethanol is widely used as a solvent both in the home and in industry[4] Study · 2008 · open source
    because of the fast evaporation of the alcohol[4] Study · 2008 · open source
    cosmetics like hairsprays or mouthwashes[5] Study · 2008 · open source

What it does

  • It helps other ingredients get into the skin (a penetration enhancer). That can help an active work, and it also lets in unwanted substances more easily.

    Well establishedskin2 sourcesHide
    Topically applied, ethanol can act as a penetration enhancer.[1] US Cosmetic Ingredient Review expert panel · 2008 · open source
    topically applied ethanol acts as a skin penetration enhancer and may facilitate the transdermal absorption of xenobiotics[5] Study · 2008 · open source
  • For comparison: alcohol hand rubs irritate the skin less than washing with soap (a detergent).

    Good evidenceskinSourceHide
    Alcohol-based hand rubs cause less skin irritation than hand washing[6] Study · 2007 · open source

Downsides and safety

  • It can dry the skin’s surface. In patch tests, alcohols lowered skin hydration but did not damage the barrier or cause redness.

    Good evidenceSourceHide
    We found no significant change in skin barrier or erythema induced by the alcohols in the patch tests, whereas skin hydration decreased significantly.[6] Study · 2007 · open source
  • On skin that is already irritated it can sting or burn. This is not an allergy, and it does not harm the skin further.

    Good evidenceSourceHide
    If the skin is pre-irritated, e.g. by detergents or water, alcohols can cause a burning sensation which is, however, not an allergic reaction and does not further harm the skin.[7] Study · 2008 · open source
  • Some people react more, especially those whose bodies break alcohol down slowly (aldehyde dehydrogenase deficiency).

    Some evidenceSourceHide
    Ethanol use is associated with skin irritation or contact dermatitis, especially in humans with an aldehyde dehydrogenase (ALDH) deficiency.[5] Study · 2008 · open source
  • No evidence so far links using it on the skin with skin cancer.

    Some evidenceSourceHide
    So far there is a lack of evidence to associate topical ethanol use with an increased risk of skin cancer.[5] Study · 2008 · open source

Where it works

SurfaceOuter layer(stratum corneum)Living layer(epidermis)Dermis

On the skin’s surface, where it evaporates; on the way it helps other ingredients into the skin.

Well establishedSourceHide
Topically applied, ethanol can act as a penetration enhancer.[1] US Cosmetic Ingredient Review expert panel · 2008 · open source

Rules

European Union

  • No EU limit: it is not on the regulation’s lists of banned or restricted substances, preservatives or UV filters.

    How we checkedHide
    We searched Annexes II to VI of the EU regulation (consolidated text of 18 May 2026): no entry.open the list

United States

  • Not on the FDA’s list of prohibited or restricted cosmetic ingredients. In the US, cosmetics and their ingredients (other than colour additives) don’t need FDA approval before sale.

    SourceHide
    Under U.S. law, cosmetic products and ingredients, other than color additives, do not need FDA approval before they go on the market[8] US Food and Drug Administration · open source
    We searched the FDA’s list of prohibited and restricted cosmetic ingredients: no entry.open the list
  • The US expert panel found it safe with the usual denaturants (such as denatonium benzoate); data were not enough for a few others (quassin, brucine).

    2 sourcesHide
    The Panel considered the available data for Denatonium Benzoate and SD Alcohol 40-B to be sufficient to support the safety of these ingredients in cosmetics.[1] US Cosmetic Ingredient Review expert panel · 2008 · open source
    The available data, however, were not sufficient to support the safety of Quassin, Brucine, and Brucine Sulfate[1] US Cosmetic Ingredient Review expert panel · 2008 · open source

Sources

  1. Final report of the safety assessment of Alcohol Denat., including SD Alcohol 3-A, SD Alcohol 30, SD Alcohol 39, SD Alcohol 39-B, SD Alcohol 39-C, SD Alcohol 40, SD Alcohol 40-B, and SD Alcohol 40-C, and the denaturants, Quassin, Brucine Sulfate/Brucine, and Denatonium Benzoate International journal of toxicology, 2008US Cosmetic Ingredient Review expert panel
  2. PubChem: Ethanol (CID 702), physical description NCBI PubChemPubChem (US National Library of Medicine)
  3. PubChem: Cetyl alcohol (CID 2682), physical description NCBI PubChemPubChem (US National Library of Medicine)
  4. Safety evaluation of topical applications of ethanol on the skin and inside the oral cavity Journal of Occupational Medicine and Toxicology (London, England), 2008Study
  5. Safety evaluation of topical applications of ethanol on the skin and inside the oral cavity Lachenmeier DW, Journal of occupational medicine and toxicology (London, England), 2008Study
  6. How irritant is alcohol? Löffler H et al., The British journal of dermatology, 2007Study
  7. Hand disinfection: how irritant are alcohols? Löffler H et al., The Journal of hospital infection, 2008Study
  8. Prohibited & Restricted Ingredients in Cosmetics | FDA US Food and Drug Administration

Checked against these sources on 4 November 2026. Spot a mistake? Tell us.